Summary:
The article explores Postural Orthostatic Tachycardia Syndrome (POTS) and Inappropriate Sinus Tachycardia (IST) complexities, emphasizing lifestyle modifications and diverse pharmacological options. Pediatric POTS often has a favorable prognosis, but IST long-term outcomes are uncertain. Acknowledging pathogenesis gaps, an interdisciplinary approach prioritizes personalized care for these chronic, underdiagnosed conditions.
Main Points:
- POTS and IST Complexity: Management involves lifestyle changes and targeted pharmacological interventions, addressing fluid and sodium intake, physical exercises, and cautious exercise introduction in post-COVID cases.
- Pharmacological Options: Beta-blockers like metoprolol, midodrine, pyridostigmine, and ivabradine are considered, with varied responses among individuals.
- Pediatric Prognosis: POTS prognosis is generally good in adolescents, while long-term prognoses for pediatric IST remain uncertain.
- Interdisciplinary Approach: An interdisciplinary approach is crucial, assessing cases individually and prioritizing lifestyle modifications.
- Pathogenesis Challenges: Limited understanding of POTS and IST pathogenesis hinders therapeutic advancements
The exact pathogenesis of these two syndromes has not yet been fully elucidated, but it is likely that POTS and IST have many aspects in common..
Long Covid The Answers
Source:
https://link.springer.com/article/10.1007/s40588-024-00217-w
Spera FR, Mistrulli R, Salerno L, Vannini F, Muthukkattil ML, Falcetti R, Segal T, Barbato E, Buonsenso D. Post-COVID Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia in the Pediatric Population. Current Clinical Microbiology Reports. 2024 Jan 27:1-1.