SOURCE: Khullar, D., Zhang, Y., Zang, C. et al. Racial/Ethnic Disparities in Post-acute Sequelae of SARS-CoV-2 Infection in New York: an EHR-Based Cohort Study from the RECOVER Program. J GEN INTERN MED 38, 1127–1136 (2023).
Summary:
In this study, researchers defined Post-Acute Sequelae of SARS-CoV-2 (PASC) using a pragmatic approach, considering 137 potential diagnostic categories. They analyzed Electronic Health Record (EHR) data from a diverse patient population in New York City to investigate racial/ethnic disparities in new symptoms and conditions among COVID-19 patients. The findings revealed significant differences in PASC incidence based on race/ethnicity, highlighting disparities in post-COVID conditions. The study emphasized the need for further research to explore the underlying reasons for these disparities and to assess the generalizability of the findings to other regions in the United States.
1. PASC Definition:
- Defined signs and symptoms of Post-Acute Sequelae of SARS-CoV-2 (PASC) using a pragmatic approach.
- Reviewed literature, clinical expert input, and data-driven methods to identify 137 possible PASC diagnostic categories.
2. Sample Selection:
- Analyzed Electronic Health Record (EHR) data from diverse NYC patient population.
- Examined racial/ethnic disparities in new symptoms and conditions among hospitalized and non-hospitalized COVID-19 patients.
3. Findings:
- Identified significant differences in PASC incidence based on race/ethnicity.
- Highlighted disparities in post-COVID conditions that require further investigation.
4. Implications:
- Suggested future research to explore reasons behind disparities and assess generalizability to other regions in the USA.
Conclusion:
This research sheds light on the importance of understanding and addressing racial/ethnic disparities in post-acute sequelae of COVID-19. By identifying differences in PASC incidence among diverse patient populations, the study underscores the need for targeted interventions and healthcare strategies to mitigate disparities and improve outcomes for all individuals affected by long-term COVID-19 complications.
Reference: Nat Med. Published online February 7, 2022:1-8.
Understanding and addressing racial/ethnic disparities in post-acute sequelae of COVID-19 is crucial for developing targeted interventions and improving outcomes for all affected individuals.
Dr. Funmi Okunola MD
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