SOURCE: Patel, M.A., Knauer, M.J., Nicholson, M. et al. Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism. Mol Med 28, 122 (2022).
Summary:
The study compared vascular transformation biomarkers in Long-COVID patients, finding significantly elevated levels of ANG-1 and P-SEL. These biomarkers showed excellent diagnostic potential, with machine learning identifying them as key in Long-COVID classification. ANG-1 was associated with female sex and lack of disease interventions in Long-COVID, suggesting a potential diagnostic profile for the condition.
Main Points:
- Elevated levels of ANG-1 and P-SEL in Long-COVID patients.
- Excellent diagnostic potential of ANG-1 and P-SEL.
- Machine learning identified ANG-1/P-SEL as crucial in Long-COVID classification.
“The molecules are critical for vascular transformation and suggest they play a wound-healing role in the Long-COVID patients.”
Long Covid The Answers
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