Biomarkers
A study on long Covid patients revealed persistent immune activation and potential virus presence in various organs even years after infection. The research utilized imaging techniques to identify immune activation in the brain, spinal cord, lungs, and gut wall. The findings suggest a need for further investigation into treatments targeting leftover virus and immunomodulating therapies....
with further research existing treatments targeting the eradication/reduction of these type of autoantibodies for Long COVID could be used and biomarkers (blood tests to show the presence of Long COVID) could be developed to identify these autoantibodies in Long Haulers who have these types of neurological symptoms, particularly those with chronic pain.
Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series
Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism - Molecular Medicine
Identifying and validating diverse immune cells, cytokines, and plasma proteins as potential biomarkers for Long COVID is crucial for improving diagnosis and treatment, highlighting the need for further exploration of LC's complex etiologies through symptom clusters or sex stratification.
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
arious components such as Antithrombin III, Complement C5, and Factor B were measured at different intensities and fold changes, with a follow-up at 6 months. The study aimed to identify biomarkers associated with Long Covid and recovery.
Researchers investigated immune and hormonal differences in individuals with Long COVID compared to those without. They found significant variations, including higher levels of specific immune cells, stronger antibody responses to SARS-CoV-2 and Epstein-Barr virus (EBV), and lower levels of the stress hormone cortisol in Long COVID patients.